Lyrica is the trade name for a drug called pregabalin. Pregabalin is an anticonvulsant (anti-seizure) drug that is often used to treat neuropathic pain as well as partial seizures that are common in temporal lobe epilepsy. In Europe, pregabalin is also approved to treat generalized anxiety disorder. Studies at the University of Kentucky reported about significant improvements in sleep quality, as well as quality of life, also were noted. When sleep problems are reduced, and sleep becomes more refreshing, musculoskeletal tissues are better able to heal, which reduces pain and improves the quality of life.
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Pregabalin has been approved to treat epilepsy, diabetic neuropathy pain, and post-herpetic neuralgia (pain after shingles). In addition, pregabalin has been approved in the U.S to treat fibromyalgia, a condition where there is pain in muscles and connective tissue as well as widespread pain and a heightened and painful response to touch. Fibromyalgia, which affects millions of people, causes not only pain around the joints, but also tenderness in muscles and nerves, as well as sleep problems that lead to symptoms of severe fatigue. The widespread pain and severe fatigue can disrupt the ability to function at full capacity on a daily basis. Altered function of the central nervous system is thought to be a possible cause.
The most prevalent side effect of pregabalin is dizziness or drowsiness, which occurs in more than 10% of patients. Between one and ten percent of patients experience visual problems, lack of coordination in muscle movements, disorder of speech, tremor, lethargy, memory problems, euphoria, constipation, dry mouth, peripheral swelling, loss of sex drive, erectile dysfunction, and weight gain. The manufacturer of Lyrica warns of potential dangerous interactions with the following drugs: Opioids, Benzodiazepines, Barbiturates , Alcohol, Any drugs that depress the central nervous system.
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