Glucophage is used to control the amount of sugar in the blood in people with diabetes mellitus. Glucophage can be used in type 1 diabetes, also called insulin dependent diabetes or juvenile onset diabetes, when insulin alone is not enough to control blood glucose levels. Type 2 diabetes is also called non-insulin dependent diabetes mellitus (NIDDM) or maturity onset diabetes. Glucophage is especially useful in those who are overweight, when diet and exercise are not enough to lower high blood glucose levels
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Glucophage lowers high blood glucose (hyperglycaemia) by helping your body make better use of the insulin produced by your pancreas. People with type 2 diabetes are unable to make enough insulin or their body does not respond properly to the insulin it does make. This causes a build up of glucose in the blood, which can lead to serious medical problems. Long-term hyperglycaemia can lead to heart disease, blindness, kidney damage, poor blood circulation and gangrene.
The dose varies from person to person. Your doctor will decide the right dose for you. The usual starting dose for adults is 500 mg one to two times a day. Your doctor may increase or decrease the dose, depending on your blood glucose levels. The maximum recommended dose is 1000 mg three times a day. The elderly and people with kidney problems may need smaller doses.
Do not take Glucophage if you are allergic to: medicines containing metformin or any other biguanide or any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include skin rash, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath. Insulin is more suitable for controlling blood glucose during pregnancy. Your doctor will replace Glucophage with insulin while you are pregnant.
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